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Author(s): Isha Agrawal1, Pratik Jangde2, Mayank Bhardwaj3, Alka Saxena4, Bharti Sahu5, Andrea Pereira6, Varaprasad Kolla7

Email(s): 1, 2, 3, 4, 5, 6, 7annpereira@gmail.com

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    1Edward and Cynthia Institute of Public health, Mangalore
    2Ameliorate Biotech, Bangalore
    3Acube Labs, Lucknow
    4Acube Labs, Lucknow
    5Seth Phoolchand Agrawal Smriti Mahavidhyalay, Raipur
    6Amity University Raipur
    *Corresponding Author Email- annpereira@gmail.com

Published In:   Volume - 6,      Issue - 1,     Year - 2024

DOI: 10.52228/NBW-JAAB.2024-6-1-5  

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ABSTRACT:
The skin is the protective outermost covering of the human body. It is highly exposed to the external environment making it prone to harsh changing environmental conditions, wide range of organisms and hence infections. The long term usage of chemical preparations to protect the skin can be very harmful. The use of plant parts/ herbs in medicine has been an traditional Indian practice. Phytochemicals found in plant extracts demonstrate antimicrobial activity that help fight infections and are long-term safe for use without any side effects. In this research we have prepared and evaluated a polyherbal ointment. Water-based extracts of raw turmeric (Curcuma longa), nutmeg (Myristica fragrans), marigold (Calendula officinalis), neem (Azadirachta indica), and orange (Citrus sinensis) peel were prepared. Alkaloids, saponins, and tannins were among the phytochemicals found in the extracts. Their susceptibility to antibiotics was examined against Staphylococcus aureus, with Ciprofloxacin as a positive control. All extracts demonstrated antibacterial activity with a varying Zone of inhibition. The herbal ointment was prepared using all the extracts after determining their Minimum Inhibitory Concentrations. The evaluated herbal ointment demonstrated antibacterial sensitivity against Staphylococcus aureus and Escherichia coli. Further, the formulated polyherbal ointment demonstrated high antibacterial sensitivity against skin bacteria when compared to a few commercially available creams. Further, when compared to a few commercially available creams the formulated polyherbal ointment demonstrated higher antibacterial activity.

Cite this article:
Isha Agrawal, Pratik Jangde, Mayank Bhardwaj, Alka Saxena, Bharti Sahu, Andrea Pereira, Varaprasad Kolla (2024) A Study on Polyherbal Skin Ointment: Formulation and Evaluation. NewBioWorld A Journal of Alumni Association of Biotechnology, 6(1): 33-41.DOI: https://doi.org/10.52228/NBW-JAAB.2024-6-1-5


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