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Author(s): Ramniwas1, Komal Gupta2, Ankita Gupta3, Aakanksha Sinha4, S.J. Daharwal*5

Email(s): 1, 2, 3, 4, 5daharwalresearch@rediffmail.com


    1University Institute of Pharmacy Pt. Ravishankar Shukla University Raipur, Chhattisgarh, India
    2University Institute of Pharmacy Pt. Ravishankar Shukla University Raipur, Chhattisgarh, India
    3University Institute of Pharmacy Pt. Ravishankar Shukla University Raipur, Chhattisgarh, India
    4University Institute of Pharmacy Pt. Ravishankar Shukla University Raipur, Chhattisgarh, India
    5University Institute of Pharmacy Pt. Ravishankar Shukla University Raipur, Chhattisgarh, India
    *Corresponding Author Email- daharwalresearch@rediffmail.com

Published In:   Volume - 4,      Issue - 2,     Year - 2022

DOI: 10.52228/NBW-JAAB.2022-4-2-4  

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The antiemetic drug ondansetron is used to treat nausea and vomiting. the creation of a straight forward, quick, affordable, accurate, and exact approach that has been approved for the estimation of ondansetron in pharmaceutical dose form and bulk form. Whether ondansetron is being estimated in pharmaceutical dose form or in bulk, the current study mostly focuses on analytical methodologies and a few tested methods. Since they enable us to employ cutting-edge analytical equipment to collect both qualitative and quantitative data, analytical methods are crucial for determining compositions. These methods aid in comprehending critical process factors and reducing the detrimental influence they have on accuracy and precision. Analytical technique development is required to uphold strict commercial product quality standards and to comply with regulatory constraints. To maintain high commercial product quality standards and to adhere to norms and regulations, analytical technique development is necessary. Regulatory organizations have created policies and procedures for granting authorization, authentication, and registration in response to the reference.

Cite this article:
Ramniwas, Komal Gupta, Ankita Gupta, Aakanksha Sinha and S.J. Daharwal (2022) A Review on various analytical methodology for Ondansetron. NewBioWorld A Journal of Alumni Association of Biotechnology,4(2):18-24.DOI: https://doi.org/10.52228/NBW-JAAB.2022-4-2-4

Anthony M, Sorkin EM 1993. Ondansetron an update of its therapeutic use in chemotherapy-induced and post operative nausea and vomiting. Drugs; 45:931-52.

Balint, A., Silvia, I.M.R.E., Bondoroi-Papp, Z. and Muntean, D.L., 2018. Development of a new rp-hplc method for ondansetron determination in injectable formulations. The Medical-Surgical Journal, 122(1), pp.207-212.

Deshmukh, T.B., Deo, S.S., Inam, F., Lambat, T.L., Gurubaxani, S.B. and Choudhari, A.V., 2015. Development and validation of Ondansetron hydrochloride in pharmaceutical dosage form by RP-HPLC method. Indian Journal of Advances in Science Engineering and Technology, 1, pp.15-20.

Gupta, P.K., Ramisetti, N.R., Cecchi, T., Swain, S., Patro, C.S. and Panda, J., 2018. An overview of experimental designs in HPLC method development and validation. Journal of Pharmaceutical and Biomedical Analysis, 147, pp.590-611.

Gupta, V., Jain, A.D.K.J., Gill, N.S. and Guptan, K., 2012. Development and validation of HPLC method-a review. International Research Journal of Pharmaceutical and Applied Sciences, 2(4), pp.17-25.

Huddart, R., Altman, R.B. and Klein, T.E., 2019. PharmGKB summary: Ondansetron and tropisetron pathways, pharmacokinetics and pharmacodynamics. Pharmacogenetics and Genomics, 29(4), p.91.

Khatal, L., More, H., Jadhav, A., Kuchekar, B., Dhaneshwar, S. And Polawar, A., 2014. Validated Hplc and Hptlc Method for Simultaneous Quantitation of Ondansetron Hydrochloride and Paracetamol in Bulk Drug and Formulation.

Meyyanathan, S.N., Venkatesh, D.N., Krishnaveni, N., Babu, B., Jeyaprakash, M.R., Raja, R.B., Hemnath, E. and Suresh, B., 2012. A RP-HPLC method for simultaneous estimation of ondansetron and ranitidine in pharmaceutical formulation. International Journal of Health and Allied Sciences, 1(2), p.129.

Mujtaba, A., Kohli, K., Ali, J. and Baboota, S., 2013. Development of HPTLC method for the estimation of ondansetron hydrochloride in bulk drug and sublingual tablets. Drug Testing and Analysis, 5(2), pp.122-125.

Patel, R.B., Patel, M.R., Bhatt, K.K. and Patel, B.G., 2010. HPTLC method development and validation: quantification of paliperidone in formulations and in vitro release study. Analytical Methods, 2(5), pp.525-531.

Patra S, Choudhury AA, Kar RK, Barik BB. Spectrophotometric method for ondansetron hydrochloride. Indian J Pharm Sci 2007; 69(6): 840-41. Edn, Merck and Company, Inc., pg. 1224.

Pharmacopeia, Indian. Vol. – 3 Indian Commission. Ghaziabad, Govt. of India: Ministry of Health and Family Welfare, 2014: 2380-2381.

Prasad CVN, Parihar C, Sunil K and Parimoop.P, 1989. Simultaneous determination of tinidazole- clotrimazole and tinidazole- norfloxacin in combined tablet preparations with other drugs. Journal of the association of official Analytical Chemists;72(3): 432-435.

Rakam, G.K., Mallik, A. and Sucharitha, C., 2022. Method Development and Validation of Reverse Phase High Performance Liquid Chromatography Method for Estimation of Ondansetron and Pantoprazole in their Tablet Dosage Form. Indian Journal of Pharmaceutical Sciences, 84(2), pp.483-192

Raval, P.B., Puranik, M., Wadher, S.J. and Yeole, P.G., 2008. A validated HPTLC method for determination of ondansetron in combination with omeprazole or rabeprazole in solid dosage form. Indian Journal of Pharmaceutical Sciences, 70(3), p.386.

Ravi Kumar P, Murali Krishna M, Bhanu prakash P, Anil kumar B and Madhusudhan P 2006. Derivative Spectrophotometric Estimation of Ondansetron and Paracetamol. E-J Chem; 3(12): 134-36.

Ravisankar, P, Gowthami, S and Rao, GD, 2014. A review on analytical method development. Indian Journal of Research in Pharmacy and Biotechnology. ;2(3):1183.

Raza A, Ijaz AS, Atta-ur-Rehman, Rasheed 2007. Spectrophotometric determination of ondansetron hydrochloride in pharmaceutical bulk and dosage forms. J Chin Chem Soc; 54: 223-27.

Roila, F. and Del Favero, A., 1995. Ondansetron clinical pharmacokinetics. Clinical pharmacokinetics, 29(2), pp.95-109.

Saraya, R.E., Salam, R.A.A. and Hadad, G.M., 2018. Stability-indicating high-performance thin-layer chromatographic determination of ondansetron in pure form and pharmaceutical formulations. JPC-Journal of Planar Chromatography-Modern TLC, 31(2), pp.122-128.

Stevens, A.J., Woodman, R.J. and Owen, H., 2015. The effect of ondansetron on the efficacy of postoperative tramadol: a systematic review and meta‐analysis of a drug interaction. Anaesthesia, 70(2), pp.209-218.

Suknuntha, K., Wattanapoka, K., Poonpattanachai, P., Titipornwanich, N. and Sripakdee, W., 2022. Compatibility and Physical Properties of Dexamethasone-Ondansetron Intravenous Admixture. Hospital Pharmacy, 57(5), pp.666-672.

Tanveer, S., Ahmad, M., Minhas, M.U., Ahmad, A. and Khan, K.U., 2021. Chitosan-PVA-co-poly (2-acrylamido-2-methylpropane sulfonic acid) cross-linked hybrid IPN-nanogels for transdermal delivery of ondansetron; synthesis, characterization and toxicological evaluation. Polymer-Plastics Technology and Materials, 60(17), pp.1913-1934.

The United State Pharmacopoeia, 24 th ed. Philadelphia: National Publishing; 2000. p. 1218.

Tramèr, M.R., Moore, R.A., Reynolds, D.J.M. and McQuay, H.J., 1997. A quantitative systematic review of ondansetron in treatment of established postoperative nausea and vomiting. BMJ, 314(7087), p.1088.

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