Abstract View

Author(s): Srishti Verma1, Samay Tirkey2, Anushruti Satra3, Kamlesh Kumar Shukla*4

Email(s): 1srishtisipi@gmail.com, 2samay6789@gmail.com, 3anushrutisatra21@gmail.com, 4kshukla26@yahoo.co.in


    1School of Studies in Biotechnology, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India
    2School of Studies in Biotechnology, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India
    3School of Studies in Biotechnology, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India
    4School of Studies in Biotechnology, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India
    *Corresponding Author Email- kshukla26@yahoo.co.in

Published In:   Volume - 4,      Issue - 1,     Year - 2022

DOI: 10.52228/NBW-JAAB.2022-4-1-6  

 View HTML        View PDF

Please allow Pop-Up for this website to view PDF file.

This study aimed to screen the secondary metabolites present in ten wild mushroom samples. All samples tested positive for phenols, flavonoids, and alkaloids, while six samples showed positive results for steroids and four for terpenoids. Phlobatannins were present in six samples, and glycosides were present in four. No anthraquinones were detected in any samples. In-vitro α-amylase inhibitory assay showed promising anti-diabetic potential, with inhibition ranging from 12.34 ± 0.50 to 93.86 ± 0.12% among the tested mushrooms. Samples 1M and 3M exhibited high inhibitory activity against α-amylase. These findings suggest that these wild mushrooms could be utilized to develop novel nutraceuticals with potential human health benefits.

Cite this article:
Srishti Verma, Samay Tirkey, Anushruti Satra, Kamlesh Kumar Shukla (2022) Secondary Metabolites Screening of Wild Mushrooms and Assessment of their In-Vitro Anti-Diabetic Property. NewBioWorld A Journal of Alumni Association of Biotechnology,4(1):28-34.DOI: https://doi.org/10.52228/NBW-JAAB.2022-4-1-6

Ambikanandan, M., & Lalan, M. S. (2009). Role of natural polysaccharides in treatment and control of diabetes. Chemistry and medicinal value, 347-373.

Barros, L., Cruz, T., Baptista, P., Estevinho, L. M., & Ferreira, I. C. (2008). Wild and commercial mushrooms as source of nutrients and nutraceuticals. Food and Chemical Toxicology, 46(8), 2742-2747.

Boruta, T. (2018). Uncovering the repertoire of fungal secondary metabolites: From Fleming's laboratory to the International Space Station. Bioengineered, 9(1), 12-16.

CFR Ferreira, I., A Vaz, J., Vasconcelos, M. H., & Martins, A. (2010). Compounds from wild mushrooms with antitumor potential. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 10(5), 424-436.

De Silva, D. D., Rapior, S., Hyde, K. D., & Bahkali, A. H. (2012). Medicinal mushrooms in prevention and control of diabetes mellitus. Fungal Diversity, 56, 1-29.

Deveci, E., Çayan, F., Tel-Çayan, G., & Duru, M. E. (2021). Inhibitory activities of medicinal mushrooms on α-amylase and α-glucosidase-enzymes related to type 2 diabetes. South African Journal of Botany, 137, 19-23.

Dias, D. A., Urban, S., & Roessner, U. (2012). A historical overview of natural products in drug discovery. Metabolites, 2(2), 303-336.

Evans, W. C. (2009). Trease and Evans' pharmacognosy. Elsevier Health Sciences.

Ha, J. W., Kim, J., Kim, H., Jang, W., & Kim, K. H. (2020). Mushrooms: An important source of natural bioactive compounds. Natural Product Sciences, 26(2), 118-131.

Jeong, Y. T., Yang, B. K., Jeong, S. C., Kim, S. M., & Song, C. H. (2008). Ganoderma applanatum: a promising mushroom for antitumor and immunomodulating activity. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 22(5), 614-619.

Joseph, B. S., Kumbhare, P. H., & Kale, M. C. (2013). Preliminary phytochemical screening of selected Medicinal Plants. Int. Res. J. of Science & Engineering, 1(2), 55-62.

Keller, N. P., Turner, G., & Bennett, J. W. (2005). Fungal secondary metabolism—from biochemistry to genomics. Nature Reviews Microbiology, 3(12), 937-947.

Kumar, K., Mehra, R., Guiné, R. P., Lima, M. J., Kumar, N., Kaushik, R. & Kumar, H. (2021). Edible Mushrooms: A comprehensive review on bioactive compounds with health benefits and processing aspects. Foods, 10(12), 2996.

Lindequist, U., Niedermeyer, T. H., & Jülich, W. D. (2005). The pharmacological potential of mushrooms. Evidence-based complementary and alternative medicine, 2(3), 285-299.

Lo, H. C., & Wasser, S. P. (2011). Medicinal mushrooms for glycemic control in diabetes mellitus: history, current status, future perspectives, and unsolved problems. International journal of medicinal mushrooms, 13(5).

Muszyńska, B., Sułkowska-Ziaja, K., & Ekiert, H. (2013). Phenolic acids in selected edible basidiomycota species: Armillaria mellea, Boletus badius, Boletus edulis, Cantharellus cibarius, Lactarius deliciosus and Pleurotus ostreatus. Acta Scientiarum Polonorum. Hortorum Cultus, 12(4).

Nowak, R., Olech, M., & Nowacka, N. (2014). Plant polyphenols as chemopreventive agents. Polyphenols in human health and disease, 1289-1307.

Öztürk, M., Tel-Çayan, G., Muhammad, A., Terzioğlu, P., & Duru, M. E. (2015). Mushrooms: a source of exciting bioactive compounds. Studies in natural products chemistry, 45, 363-456.

Papoutsis, K., Zhang, J., Bowyer, M. C., Brunton, N., Gibney, E. R., & Lyng, J. (2021). Fruit, vegetables, and mushrooms for the preparation of extracts with α-amylase and α-glucosidase inhibition properties: A review. Food Chemistry, 338, 128119.

Qiang, X., YongLie, C., & QianBing, W. (2009). Health benefit application of functional oligosaccharides. Carbohydrate polymers, 77(3), 435-441.

Sato, M., Tai, T., Nunoura, Y., Yajima, Y., Kawashima, S., & Tanaka, K. (2002). Dehydrotrametenolic acid induces preadipocyte differentiation and sensitizes animal models of noninsulin-dependent diabetes mellitus to insulin. Biological and Pharmaceutical Bulletin, 25(1), 81-86.

Sheel, R., Nisha, K., & Kumar, J. (2014). Preliminary phytochemical screening of methanolic extract of Clerodendron infortunatum. IOSR Journal of Applied Chemistry, 7(1), 10-13.

Stojkovic, D., Smiljkovic, M., Ciric, A., Glamoclija, J., Van Griensven, L., Ferreira, I. C., & Sokovic, M. (2019). An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes. South African Journal of Botany, 120, 100-103.

Suman, K. R., Venkateshwar, C., Samuel, G., & Gangadhar, R. S. (2013). Phytochemical Screening of some compounds from plant leaf extracts of Holoptelea integrifolia (Planch.) and Celestrus emarginata (Grah.) used by Gondu tribes at Adilabad District, Andhrapradesh, India. Int. J. Eng. Sci. Inv, 2(8), 65-70.

Tiwari, P., Kumar, B., Kaur, M., Kaur, G., & Kaur, H. (2011). Phytochemical screening and extraction: a review. Internationale pharmaceutica sciencia, 1(1), 98-106.

Verma, S., Valvi, V., & Shukla, K. K. (2022). Screening Some Extracellular Enzymes of Wild Mushrooms from Pt. Ravishankar Shukla University Campus. Journal of Ravishankar University, 35(1), 42–52.

Xiao, C., Wu, Q., Tan, J., Cai, W., Yang, X. B., & Zhang, J. M. (2011). Inhibitory effects on α-glucosidase and hypoglycemic effects of the crude polysaccharides isolated from 11 edible fungi. J Med Plants Res, 5(32), 6963-6967.

Related Images:

Recent Images

Therapeutic Use of Some Common Medicinal Plants for the Treatment of Major Life Style Diseases of Chhattisgarh
Butterflies and Their Conservation Status on the Campus of Sant Guru Ghasidas Government P.G. College Kurud, Chhattisgarh, India
Fermentation of Tomato Juice with S. cerevisiae has enhanced nutrition and shelf-life
Review on double haploid in rice plant (Oryza sativa L.)
A  Review of Clinical Aspect of Dhatura: According to Ayurveda
An aphid transmitted banana bunchy top disease of banana and its detection: A Review
Comparative Evaluation of In Vitro Antimicrobial Efficacy of different Species of Curcuma against Human Pathogenic Bacteria
Phytoremediation: A Sustainable Approach to Combat Heavy Metal Contaminated Soil - A Review
A brief overview of plant abiotic stresses
Formulation and Evaluation of Herbal Toothpaste against Biofilm Producing Staphylococcus aureus


Recomonded Articles:

Author(s): Pingla Sen; Anjali Kosre; Deepali Koreti; Nagendra Kumar Chandrawansi; Shailesh Kumar Jadhav

DOI: 10.52228/NBW-JAAB.2021-3-2-2         Access: Open Access Read More

Author(s): Sharon Khalkho; Deepali Koreti; Anjali Kosre; S.K. Jadhav; Nagendra Kumar Chandrawanshi

DOI: 10.52228/NBW-JAAB.2021-3-1-2         Access: Open Access Read More

Author(s): Nagendra Kumar Chandrawansh; Devendra Kumar Tandia; S. K. Jadhav

DOI: 10.52228/NBW-JAAB.2019-1-1-2         Access: Open Access Read More

Author(s): Khemraj Sahu*; Pritika Pradhan; Nagendra Kumar Chandrawanshi

DOI: 10.52228/NBW-JAAB.2022-4-2-3         Access: Open Access Read More

Author(s): Srishti Verma; Samay Tirkey; Anushruti Satra; Kamlesh Kumar Shukla*

DOI: 10.52228/NBW-JAAB.2022-4-1-6         Access: Open Access Read More